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My experience so far:
Started allopurinol 4 months ago. My doctor said we'd start with the 300mg dose immediately. He said he'd seen no real advantage in starting with lower dosis and slowly increase, other than discard allergies, which by the way are rather unusual (in his own words). He was very confident that the treatment will be just fine, he just said “nothing bad will happen to you, don't worry. I bet you won't even have a new flare.”
Most visible results:
1. No flares. UA levels down to 5 from 9.2.
2. For the first week I felt drowsiness but it eventually went away. Guess my body was just adapting.
3. Sometimes I do feel like I've read an entire book in a badly illuminated room. Maybe I'm just working too hard…, it's hard to tell whether this symptom is due to allopurinol or not.
4. Headaches every two to three days. These too seemed to disappear after an adjustment period (1 month).
5. Less sleep hours. This also improved on time. Completely normal now.
Regards.
